石哲
医学博士/博士后
zhezhe1106@163.com
毕业于北京协和医学院，卢森堡国家健康研究院访问学者，中南大学精神卫生研究所特聘研究员。
目前担任中国生理学会转化神经科学专委会委员，中国药物滥用防治协会成瘾与脑科学分会委员，中国康复医学会脑功能检测与调控康复专委会委员，中国实验动物学会动物资源鉴定与评价工作委员会委员。
多年来一直从事精神药理学研究。主要研究兴趣为利用非人灵长类与啮齿类动物模型研究应激(包括军事与航天特因环境应激)所致精神疾病发病机制与创新药物研发。
先后在《Biological Reviews》、《Molecular Psychiatry》、《Pharmacological Research》与《Molecular Neurobiology》等 SCI期刊发表论文三十余篇。
主持和参加国家级与省部级课题多项，获国家专利3项。
近五年第一/共同第一/通讯/共同通讯作者发表文章
- Zhe Shi, Meng Qin, Lu Huang, Tao Xu, Ying Chen, Qin Hu, Sha Peng, Zhuang Peng, Lina Qu, Shanguang Chen, Qinhui Tuo, Duanfang Liao, Xiaoping Wang, Renrong Wu*, Tifei Yuan*, Yinghui Li, Xinmin Liu, Human torpor: translating insights from nature into manned deep space expedition. 2021, Biological Reviews, 96(2): 642-672. (SCI, IF=10.701, JCR Q1)
- Shiyu Peng#, Zhe Shi#, Dongsheng Zhou#, Xingxing Li, Xiaoli Liu, Weidi Wang, Guanning Lin, Bingxing Pan, Valerie Voon, Anthony Grace, Markus Heilig, Ma Wong, Tifei Yuan*, Reduced cortical GABABR function following chronic alcohol exposure. co-first author, 2021, Molecular Psychiatry, 26(2): 383-395. (SCI, IF=12.384, JCR Q1)
- Sha Peng, Zhuang Peng, Meng Qin, Lu Huang, Bin Zhao, Lai Wei, Jie Ning, Qin-hui Tuo, Ti-fei Yuan*, Zhe Shi*, Duan-fang Liao*, Targeting neuroinflammation, the therapeutic potential of omega-3 PUFAs in substance abuse. 2021, Nutrition, 83: 111058. (SCI, IF=3.639, JCR Q1)
- Lu Huang, Zhuang Peng, Cong Lu, Ying Chen, Jingwei Lv, Meng Qin, Duanfang Liao, Xinmin Liu, Zhe Shi*. Ginsenoside Rg1 alleviates repeated alcohol exposure-induced psychomotor and cognitive deficits. 2020, Chinese Medicine, 15: 44. (SCI, IF=2.96, JCR Q1)
- Mingchao He#, Zhe Shi#, Meng Qin, Nannan Sha, Duanfang Liao, Mansau Wong, Xiaoli Dong, Yongjun Wang, Tifei Yuan, Yan Zhang, Muscone ameliorates lps-induced depressive-like behaviors and inhibits neuroinflammation in prefrontal cortex of mice. co-first author, 2020, American journal of Chinese medicine, 48(3):559-577 (SCI, IF=3.682, JCR Q1)
- Mingchao He#, Zhe Shi#, Nannan Sha, Nan Chen, Shiyu Peng, Duanfang Liao, Mansau Wong, Xiaoli Dong, Yongjun Wang, Tifei Yuan, Yan Zhang, Paricalcitol alleviates lipopolysaccharide-induced depressive-like behavior by suppressing hypothalamic microglia activation and neuroinflammation. co-first author, 2019, Biochemical Pharmacology, May;163:1-8. (SCI, IF=4.96, JCR Q1)
- Jing Wang#, Zhe Shi#, Tao Zou, Minxu Zou, Huixian Yang, Caiping Zhang, Debiao Xiang, Limei Lin, Huiyu Liu, Deyu Fang, Duanfang Liao, A novel recombinant peptide INSR-IgG4Fc (Yiminsu) restores insulin sensitivity in experimental insulin resistance models, co-first author, 2019, Biomedicine & Pharmacotherapy, (109)1276-1286. (SCI, IF=4.545, JCR Q1)
- Zhe Shi, Youna Xie, Huixia Ren, Baixuan He, Meng Wang, Jianbo Wan, Ti-Fei Yuan*, Xiaoli Yao*, Huanxing Su*，Fish oil treatment reduces chronic alcohol exposure induced synaptic changes，2019，Addiction biology. Jul;24(4):577-589. (SCI, IF=4.223, JCR Q1)
- Zhe Shi, Ying Chen, Cong Lu, Liming Dong, Jingwei Lv, qinhui tuo, Li Qin, Shaowu Cheng, Lan-lan Bu, Na Lin, Xiaoxin Zhu*, Duan-fang Liao*, Xinmin Liu*, Resolving neuroinflammation, the therapeutic potential of the anti-malaria drug family of artemisinin, 2018, Pharmacological research, Oct;136:172-180. (SCI, IF=5.574, JCR Q1)
- Zhe Shi, Huixia Ren, Yu Peng Zhijian Huang, Ti-Fei Yuan*, Huanxing Su*, Fish oil prevents Lipopolysaccharide -induced depressive-like behavior by inhibiting neuroinflammation, 2017, Molecular Neurobiology, Nov;54(9):7327-7334. (SCI, IF=5.076, JCR Q1)
- Cong Lu#, Zhe Shi#, Xiuping Sun, Ruile Pan, Shanguang Chen, Yinghui Li, Lina Qu, Lihua Sun, Haixia Dang, Lanlan Bu, Xinmin Liu*, Kai Xin San aqueous extract improves Aβ 1-40-induced cognitive deficits on adaptive behavior learning by enhancing memory-related molecules expression in the hippocampus, co-first author, 2016, Journal of Ethnopharmacology, Apr 6;201:73-81. (SCI, IF=2.981, JCR Q1)
- Zhe Shi#, Di Wu#, Jian-Ping Yao, Xiaoli Yao, Zhijian Huang, Peng Li, Jian-Bo Wan, Chengwei He*, Huanxing Su*, Protection against Oxygen-Glucose Deprivation/Reperfusion Injury in Cortical Neurons by Combining Omega-3 Polyunsaturated Acid with Lyciumbarbarum Polysaccharide, 2016, Nutrients, 8(1), 41; doi:10.3390/nu8010041. (SCI, IF=3.55, JCR Q1)
- Zhe Shi, Huixia Ren, Chuanming Luo, Xiaoli Yao, Haitao Zeng, Peng Li, Chengwei He, Jingx Kang, Jian-Bo Wan, Ti-Fei Yuan*, Huanxing Su*, Enriched Endogenous Omega-3 Polyunsaturated Fatty Acids Protect Cortical Neurons from Experimental Ischemic Injury, 2016, Molecular Neurobiology, Epup ahead of print. (SCI, IF=6.190, JCR Q1)
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